Middletown Air Depot

Base Background

Location Middletown, Pennsylvania, 17057, United States
Years of Operation 1931-Present

Middletown Air Depot was established in 1931 and is now the Harrisburg International Airport. The site focused on aircraft maintenance and material supply, particularly during World War II. Some of the base structures were demolished for airport construction.

Known Toxins

The following chart outlines the medical conditions associated with toxic exposure at this base, classified by the strength of evidence required (strong, good or limited).* Please keep in mind that it is not a complete list.

Toxin Potential Effects
Strong Good Limited
Arsenic Potential Effects Peripheral neuropathy, Hyperkeratosis/Hyperpigmentation, Diabetes ­ Type II, Coronary artery disease, peripheral vascular disease, atherosclerosis Steatosis (fatty liver), Skeletal malformations, Renal (kidney) cancer, Raynaud's phenomenon, Pneumonitis hypersensitivity, Neural tube defects/CNS malformations, Nasal septal perforation, Myocardial ischemia, Low birth weight/Small for Gestational Age, Hypertension, Hepatoportal Sclerosis, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Congenital malformations ­ general, Cirrhosis, Cardiomyopathy, Bladder cancer, Arrhythmias, Anemia ­ hemolytic, Alopecia, Adult­-Onset Leukemias Neurosthenia (Organic affective syndrome), Myelodysplastic syndrome, Metal fume fever, Immune suppression, Hepatocellular cancer (Liver cancer), Genito­urinary malformations (includes cryptorchidism, hypospadias), Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Acute tubular necrosis
Barium Potential Effects - - Sarcoidosis, Arrhythmias
Benzene Potential Effects Myelodysplastic syndrome, Multiple myeloma, Aplastic anemia Scleroderma, Renal (kidney) cancer, Pre­term delivery, Menstrual disorders, Lymphoma non ­Hodgkin's, Autoimmune antibodies, positive ANA, Arrhythmias Peripheral neuropathy, Neural tube defects/CNS malformations, Nasopharyngeal/Sino­Nasal cancer, Lung cancer, Immune suppression, Hepatocellular cancer (Liver cancer), Cardiac congenital malformations, Breast cancer, Brain cancer ­adult, Asthma ­irritant
Cadmium Potential Effects Renal stones, Osteoporosis, Itai­itai disease, Chronic renal disease, Acute tubular necrosis Reduced Fertility Male (infertility and subfertility), Prostate cancer, Pneumonia, Nephrotic syndrome, COPD ­chronic obstructive pulmonary disease, Cardiomyopathy, Anemia ­ hemolytic Testicular cancer, Soft tissue sarcoma, Renal (kidney) cancer, Pulmonary fibrosis, Pulmonary edema, Peripheral neuropathy, Pancreatic cancer, Oral clefts (cleft lip and palate), Neural tube defects/CNS malformations, Metal fume fever, Menstrual disorders, Immune suppression, Hypoactivity, Hypertension, Genito­urinary malformations (includes cryptorchidism, hypospadias), Decreased I.Q../Mental retardation, Congenital malformation Cranio­ Facial, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Brain cancer ­adult, Autoimmune antibodies, positive ANA, Arrhythmias, ADD/ADHD, hyperactivity, Abnormal sperm (morphology, motility, and sperm count)
Carbon tetrachloride Potential Effects Steatosis (fatty liver), Cirrhosis, Acute tubular necrosis, Acute hepatocellular injury (Hepatitis) Scleroderma, Porphyria ­ toxic, Lymphoma non ­Hodgkin's, Childhood Leukemias, Autoimmune antibodies, positive ANA, Arrhythmias, Aplastic anemia, Adult­-Onset Leukemias Renal (kidney) cancer, Pancreatitis, Pancreatic cancer, Oral clefts (cleft lip and palate), Nephrotic syndrome, Melanoma, Low birth weight/Small for Gestational Age, Immune suppression, Hepatocellular cancer (Liver cancer), Brain cancer ­adult
Chlorobenzene Potential Effects - - -
Chloroethene Potential Effects - - -
Chromium Potential Effects Skin ulceration, Parkinson's disease/Movement disorders, Nasopharyngeal/Sino­Nasal cancer, Nasal septal perforation, Nasal polyps, Cholestasis, Bronchitis ­ acute, Asthma ­ allergic Stomach cancer, Pulmonary fibrosis, Psychiatric disturbances, Pneumonitis hypersensitivity, Pneumonia, Photosensitivity, Peripheral neuropathy, Decreased Coordination/ Dysequilibrium, COPD ­chronic obstructive pulmonary disease, Chronic renal disease, Bronchitis ­ acute, Brain cancer ­adult, ADD/ADHD, hyperactivity, Acute tubular necrosis Soft tissue sarcoma, Skeletal malformations, Renal (kidney) cancer, Reduced Fertility Male (infertility and subfertility), Prostate cancer, Peripheral neuropathy, Pancreatic cancer, Neurosthenia (Organic affective syndrome), Neural tube defects/CNS malformations, Metal fume fever, Immune suppression, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Esophageal cancer, Erectile dysfunction, Delayed growth, COPD ­chronic obstructive pulmonary disease, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Bladder cancer, Autoimmune antibodies, positive ANA, Arrhythmias, Adult­-Onset Leukemias, Abnormal sperm (morphology, motility, and sperm count)
Heavy metals (misc.) Potential Effects Pneumonitis hypersensitivity - Multiple myeloma, Chronic renal disease
Iron Potential Effects Bronchitis ­ chronic - Soft tissue sarcoma, Diabetes ­ Type II, Brain cancer ­adult, Alzheimer's
Lead Potential Effects Seizures, Reduced Fertility Male (infertility and subfertility), Peripheral neuropathy, Hypertension, Gout, Developmental Delay, Decreased I.Q../Mental retardation, Decreased Coordination/ Dysequilibrium, Coronary artery disease, peripheral vascular disease, atherosclerosis, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Chronic renal disease, Behavioral problems, Anemia ­ hemolytic, ADD/ADHD, hyperactivity, Abnormal sperm (morphology, motility, and sperm count) Reduced Fertility ­ Female (infertility and subfertility), Psychiatric disturbances, Pre­term delivery, Porphyria ­ toxic, Pancreatic cancer, Nephrotic syndrome, Low birth weight/Small for Gestational Age, Immune suppression, Hearing loss, Glomerulonephritis, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Delayed growth, Cardiomyopathy, Arrhythmias, Altered time to sexual maturation (accelerated or delayed puberty) Wilm's Tumor, Uterine cancer, Thyroid disorders ­Hypothyroidism, Stomach cancer, Reduced Fertility Male (infertility and subfertility), Osteoporosis, Neurosthenia (Organic affective syndrome), Lung cancer, Hepatocellular cancer (Liver cancer), Erectile dysfunction, Diabetes ­ Type II, Congenital malformation Cranio­ Facial, Colo­rectal cancer, Carcinoid, Breast cancer, Brain cancer ­adult, Bladder cancer, Alzheimer's, Altered time to sexual maturation (accelerated or delayed puberty), ALS (Lou Gehrig's disease), Abnormal sperm (morphology, motility, and sperm count)
Nickel Potential Effects Asthma ­ allergic Stomach cancer, Pulmonary fibrosis, Pulmonary edema, Nasal septal perforation, Laryngeal cancer, Immune suppression Soft tissue sarcoma, Renal (kidney) cancer, Prostate cancer, Myocardial ischemia, Myelodysplastic syndrome, Metal fume fever, Mesothelioma, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Arrhythmias
Trichloroethanes Potential Effects - - Hormonal changes (levels of circulating sex hormones ­ FSH/LH, Inhibin, and/or estrogens, progesterones, and androgens)
Trichloroethylene (TCE) Potential Effects Acute hepatocellular injury (Hepatitis) Scleroderma, Renal (kidney) cancer, Psychiatric disturbances, Lymphoma non ­Hodgkin's, Hepatocellular cancer (Liver cancer), Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Decreased Coordination/ Dysequilibrium, Cirrhosis, Childhood Leukemias, Cardiac congenital malformations, Autoimmune antibodies, positive ANA, Arrhythmias Trigeminal neuropathy, Testicular cancer, Systemic Lupus Erythematosus, Raynaud's phenomenon, Prostate cancer, Peripheral neuropathy, Pancreatitis, Pancreatic cancer, Oral clefts (cleft lip and palate), Neural tube defects/CNS malformations, Nephrotic syndrome, Multiple myeloma, Lung cancer, Low birth weight/Small for Gestational Age, Immune suppression, Hodgkin's Disease (lymphoma), Genito­urinary malformations (includes cryptorchidism, hypospadias), Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Choanal atresia, Cervical cancer, Brain cancer ­adult, Adult­-Onset Leukemias, ADD/ADHD, hyperactivity, Acute tubular necrosis
Volatile organic compounds (VOCs) Potential Effects Rhinitis ­ irritant - -
Zinc Potential Effects Skin ulceration - Testicular cancer

If you were stationed at Middletown Air Depot and later experienced adverse health effects, you may be eligible for compensation.

*Effects are according to the Center for Disease Control and Prevention’s Agency for Toxic Substances & Disease Registry unless otherwise noted.